According to Coro Coro Comics, Pokémon Black & White 2 will feature an all-new cast of characters as well as a new location.
When you first begin your adventure to train and catch ‘em all, you’ll be able to pick from newly sporty styled male and female trainers. As usual you’ll have a rival hot on your heels as well as a new second character named Akuroma described as a mysterious figure researching the strengths of Pokémon.
Two new gym leaders were mentioned too. Homika is armed with poison type Pokemon, while Shizui relies on water type monsters.
Location wise, the games will still take place in the Isshu Region however players will begin their journey in Hiougi City, in the South of Isshu.
The comic also quotes the game as being released in Japan on June 23. The rest of the world however are still in the dark.